Peptides as NS3-serine protease inhibitors of hepatitis C virus

Peptides as NS3-serine protease inhibitors of hepatitis C virus

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associ...

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Hauptverfasser: Saksena, Anil K, Girijavallabhan, Viyyoor Moopil, Lovey, Raymond G, Jao, Edwin, Bennett, Frank, McCormick, Jinping L, Wang, Haiyan, Pike, Russell E, Bogen, Stephane L, Chan, Tin-Yau, Liu, Yi-Tsung, Zhu, Zhaoning, Njoroge, F. George, Arasappan, Ashok, Parekh, Tejal, Ganguly, Ashit K, Chen, Kevin X, Venkatraman, Srikanth, Vaccaro, Henry M, Pinto, Patrick A, Santhanam, Bama, Kemp, Scott Jeffrey, Levy, Odile Esther, Lim-Wilby, Marguerita, Tamura, Susan Y, Wu, Wanli, Hendrata, Siska, Huang, Yuhua
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.