Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines

Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines

A novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines represented by the [Formula 24], [Formula 25], [Formula 26], and/or [Formula 27].

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1. Verfasser: DAIICHI SANKYO COMPANY, LIMITED
Format: Patent
Sprache:eng
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Zusammenfassung:A novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines represented by the [Formula 24], [Formula 25], [Formula 26], and/or [Formula 27].