Chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxin of

Staphylococcus aureus Staphylococcus aureus Staphylococcus aureus 32Staphylococcus aureus. The invention relates to a chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxins of and a use thereof. The chemosynthetic peptide can specifically inhibit production of the toxins of by mean...

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1. Verfasser: ZHONGCHENG INVESTMENT MANAGEMENT (SHANGHAI) CO., LTD
Format: Patent
Sprache:eng
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Zusammenfassung:Staphylococcus aureus Staphylococcus aureus Staphylococcus aureus 32Staphylococcus aureus. The invention relates to a chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxins of and a use thereof. The chemosynthetic peptide can specifically inhibit production of the toxins of by means of the binding of the RNAIII activator protein by a autocrine. The invention also relates to the use of the chemosynthetic peptide in the pharmaceutical field. The sequence general formula of the chemosynthetic cyclo-hepta modified peptide is CH-(CH)m-X-G-(CQHWWHWYC)-(R)n-Y. The results show that the modified peptide can be dissolved well in water and has good activity against the toxins of