Synthetic lethal targeting of glucose transport

The present invention provides methods for inhibiting growth and proliferation of HIF pathway proficient cells by administering GLUT1 inhibitors of the invention to HIF pathway proficient cells.

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Bibliographische Detailangaben
Hauptverfasser: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, AUCKLAND UNISERVICES LIMITED, RUGA CORPORATION
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides methods for inhibiting growth and proliferation of HIF pathway proficient cells by administering GLUT1 inhibitors of the invention to HIF pathway proficient cells.