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The present invention discloses collagen cross-linked in a micro to non-fibrillar form and at a high concentration. The cross-linked collagen gel has improved volume stability or persistence than collagen cross-linked at a neutral pH. Also disclosed are methods for preparing the inventive cross-link...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schroeder, Jacqueline Anne, Dapper, Gregory S, Olson, Kenneth C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses collagen cross-linked in a micro to non-fibrillar form and at a high concentration. The cross-linked collagen gel has improved volume stability or persistence than collagen cross-linked at a neutral pH. Also disclosed are methods for preparing the inventive cross-linked collagen and using such for augmenting soft tissues in mammals.