Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders

Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders

The invention provides methods and compositions for reducing or inhibiting net beta-amyloid peptide production and/or amyloid plaque formation. The methods and compositions involve administering a netrin-1 polypeptide or netrin-1 therapeutic to a subject in need thereof.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mehlen, Patrick, Bredesen, Dale E, Calheiros-Lourenco, Filipe, Galvan, Veronica
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Mehlen, Patrick
Bredesen, Dale E
Calheiros-Lourenco, Filipe
Galvan, Veronica
description The invention provides methods and compositions for reducing or inhibiting net beta-amyloid peptide production and/or amyloid plaque formation. The methods and compositions involve administering a netrin-1 polypeptide or netrin-1 therapeutic to a subject in need thereof.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_08329653</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>08329653</sourcerecordid><originalsourceid>FETCH-uspatents_grants_083296533</originalsourceid><addsrcrecordid>eNqNjEEKwjAQRbNxIeod5gKCWBRdF8UDuJfBmbSBJpPOJIq3twUP4Oot_nt_6XIrMYuFEiQZYCKIXHohAy8KVnNWNptGEA8YP4MEgjzgWHk2Is4hoJk8AxYmeIfSQ-KqQtxxYp2MFwMFEyVWW7uFx8F48-PKwfVyb2_bank6SMUeneKM3anZn4-HpvlD-QLYeEXv</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders</title><source>USPTO Issued Patents</source><creator>Mehlen, Patrick ; Bredesen, Dale E ; Calheiros-Lourenco, Filipe ; Galvan, Veronica</creator><creatorcontrib>Mehlen, Patrick ; Bredesen, Dale E ; Calheiros-Lourenco, Filipe ; Galvan, Veronica ; Centre National de la Recherche Scientifique ; Buck Institute for Age Research</creatorcontrib><description>The invention provides methods and compositions for reducing or inhibiting net beta-amyloid peptide production and/or amyloid plaque formation. The methods and compositions involve administering a netrin-1 polypeptide or netrin-1 therapeutic to a subject in need thereof.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8329653$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64012</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8329653$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Mehlen, Patrick</creatorcontrib><creatorcontrib>Bredesen, Dale E</creatorcontrib><creatorcontrib>Calheiros-Lourenco, Filipe</creatorcontrib><creatorcontrib>Galvan, Veronica</creatorcontrib><creatorcontrib>Centre National de la Recherche Scientifique</creatorcontrib><creatorcontrib>Buck Institute for Age Research</creatorcontrib><title>Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders</title><description>The invention provides methods and compositions for reducing or inhibiting net beta-amyloid peptide production and/or amyloid plaque formation. The methods and compositions involve administering a netrin-1 polypeptide or netrin-1 therapeutic to a subject in need thereof.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjEEKwjAQRbNxIeod5gKCWBRdF8UDuJfBmbSBJpPOJIq3twUP4Oot_nt_6XIrMYuFEiQZYCKIXHohAy8KVnNWNptGEA8YP4MEgjzgWHk2Is4hoJk8AxYmeIfSQ-KqQtxxYp2MFwMFEyVWW7uFx8F48-PKwfVyb2_bank6SMUeneKM3anZn4-HpvlD-QLYeEXv</recordid><startdate>20121211</startdate><enddate>20121211</enddate><creator>Mehlen, Patrick</creator><creator>Bredesen, Dale E</creator><creator>Calheiros-Lourenco, Filipe</creator><creator>Galvan, Veronica</creator><scope>EFH</scope></search><sort><creationdate>20121211</creationdate><title>Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders</title><author>Mehlen, Patrick ; Bredesen, Dale E ; Calheiros-Lourenco, Filipe ; Galvan, Veronica</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_083296533</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Mehlen, Patrick</creatorcontrib><creatorcontrib>Bredesen, Dale E</creatorcontrib><creatorcontrib>Calheiros-Lourenco, Filipe</creatorcontrib><creatorcontrib>Galvan, Veronica</creatorcontrib><creatorcontrib>Centre National de la Recherche Scientifique</creatorcontrib><creatorcontrib>Buck Institute for Age Research</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Mehlen, Patrick</au><au>Bredesen, Dale E</au><au>Calheiros-Lourenco, Filipe</au><au>Galvan, Veronica</au><aucorp>Centre National de la Recherche Scientifique</aucorp><aucorp>Buck Institute for Age Research</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders</title><date>2012-12-11</date><risdate>2012</risdate><abstract>The invention provides methods and compositions for reducing or inhibiting net beta-amyloid peptide production and/or amyloid plaque formation. The methods and compositions involve administering a netrin-1 polypeptide or netrin-1 therapeutic to a subject in need thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_08329653
source USPTO Issued Patents
title Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T12%3A25%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Mehlen,%20Patrick&rft.aucorp=Centre%20National%20de%20la%20Recherche%20Scientifique&rft.date=2012-12-11&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E08329653%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true