Three-branched polyethylene glycol-G-CSF conjugate

The present invention relates to three-branched PEG-G-CSF conjugate of general formula (1) in which the bonding ratio of three-branched polyethylene glycol (PEG) and G-CSF is 1:1 (mol/mol), wherein PEG has an average molecular weight of from 200 to 45,000 daltons; a pharmaceutical composition compri...

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Bibliographische Detailangaben
Hauptverfasser: Jo, Yeong-Woo, Yoo, Won-Young, Jeon, Hyun-Kyu, Choi, Yun-Kyu, Jang, Hye-In, Kim, Byong-Moon, Lee, Sung-Hee, Kang, Soo-Hyung, Yoo, Moo-Hi
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to three-branched PEG-G-CSF conjugate of general formula (1) in which the bonding ratio of three-branched polyethylene glycol (PEG) and G-CSF is 1:1 (mol/mol), wherein PEG has an average molecular weight of from 200 to 45,000 daltons; a pharmaceutical composition comprising the same, and a preparing method thereof.