Methods for inhibiting CLC-2 channel with GATX2

Compositions and methods of using scorpion venom peptide that is a ligand for ClC channels are provided. One aspect provides a pharmaceutical composition containing an amount of GaTx2 effective to inhibit ClC activity. Methods of treating a disorder or symptom of a disorder related to aberrant ClC c...

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Bibliographische Detailangaben
Hauptverfasser: McCarty, Neal, Thompson, Christopher H, Kubanek, Julia
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions and methods of using scorpion venom peptide that is a ligand for ClC channels are provided. One aspect provides a pharmaceutical composition containing an amount of GaTx2 effective to inhibit ClC activity. Methods of treating a disorder or symptom of a disorder related to aberrant ClC channel activity are also provided.