Water-soluble substrate with resistance to dissolution prior to being immersed in water

A water-soluble substrate, and more particularly a water-soluble substrate that is resistant to dissolution, and methods of making the same are disclosed. The water-soluble substrate has a first and second surface. Water-insoluble particles are applied to and partially embedded in at least one of said first and second surfaces, thereby forming protruberances on said first and/or second surface. The protruberances have an average height of from 10 nanometer to 100 micrometer, and the average distance between adjacent peaks of said protruberances is from 10 nanometer to 200 micrometer. Articles, such as pouches, made from the water-soluble substrate, are also disclosed herein.