Method of making particles for use in a pharmaceutical composition

The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Staniforth, John, Green, Matthew Michael James, Morton, David Alexander Vodden
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler. The invention also relates to compositions for inhalation prepared by the method.