Quinolinone derivatives as PARP and TANK inhibitors

1234567The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R, R, R, R, R, R, R, n, m and X have defined meanings.

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Bibliographische Detailangaben
Hauptverfasser: Vialard, Jorge Eduardo, Angibaud, Patrick René, Mevellec, Laurence Anne, Meyer, Christophe, Freyne, Eddy Jean Edgard, Pilatte, Isabelle Noëlle Constance, Roux, Bruno, Pasquier, Elisabeth Thérèse Jeanne, Bourdrez, Xavier Marc, Adelinet, Christophe Denis, Marconnet-Decrane, Laurence Françoise Bernadette, Macritchie, Jacqueline Anne, Duffy, James Edward Stewart, Owens, Andrew Pate, Storck, Pierre-Henri, Poncelet, Virginie Sophie
Format: Patent
Sprache:eng
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Zusammenfassung:1234567The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R, R, R, R, R, R, R, n, m and X have defined meanings.