Materials and methods relating to improved vaccination strategies

The invention provides novel vaccination strategies based on a prime-boost vaccination regiment. The inventors have determined improved ways of boosting an immune response in a patient previously primed or exposed to a plurality of epitopes. The improved method requires the epitopes in the boosting...

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Bibliographische Detailangaben
Hauptverfasser: Cerundolo, Vincenzo, Palmowski, Michael J, Choi, Edward Man-Lik
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides novel vaccination strategies based on a prime-boost vaccination regiment. The inventors have determined improved ways of boosting an immune response in a patient previously primed or exposed to a plurality of epitopes. The improved method requires the epitopes in the boosting phase to be administered individually, i.e. held on separate peptide constructs.