Methods for preparing pharmaceuticals by emulsion aggregation processes

A method for making a pharmaceutical by emulsion aggregation, the method including emulsifying a first pharmaceutical agent and a biodegradable resin to form a primary emulsion of pre-aggregated particles in a slurry; aggregating the pre-aggregated particles to form aggregated pharmaceutical particl...

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Bibliographische Detailangaben
Hauptverfasser: Blair, Christopher David, Lai, Zhen, Ou, Zhaoyang, Mattison, Jr, Dennis A, Dale, Philip J, Cheng, Chieh-Min
Format: Patent
Sprache:eng
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Zusammenfassung:A method for making a pharmaceutical by emulsion aggregation, the method including emulsifying a first pharmaceutical agent and a biodegradable resin to form a primary emulsion of pre-aggregated particles in a slurry; aggregating the pre-aggregated particles to form aggregated pharmaceutical particles in the slurry; and isolating the pharmaceutical particles. The method may be used to make time-released, multi-formulation, and inhalable pharmaceuticals.