Solid pharmaceutical dispersions with enhanced bioavailability

Solid pharmaceutical dispersions with enhanced bioavailability

Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.

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Bibliographische Detailangaben
Hauptverfasser: Curatolo, William J, Herbig, Scott M, Nightingale, James A. S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.