I/O forwarding technique for multi-interrupt capable devices

The method, apparatus and system of an I/O forwarding technique for multi-interrupt capable I/O devices are disclosed. In one embodiment, a method of transferring an I/O request in a cache-coherent non-uniform memory access (ccNUMA) computer system including multiple cells (e.g., each cell may include multiple processors) that are connected via a system interconnect, includes receiving an I/O request from one of the multiple processors associated with one of the multiple cells in the ccNUMA computer system, associating a processor, corresponding to a multi-interrupt capable I/O interface that is servicing the I/O request, located in the one of the multiple cells as a lead processor, and executing an I/O initiation path and a completion path associated with the received I/O request on the lead processor upon associating the lead processor corresponding to the multi-interrupt capable I/O interface.