Raf inhibitors

The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

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Bibliographische Detailangaben
Hauptverfasser:	Schoop, Andreas, Backes, Alexander, Vogt, Joachim, Neumann, Lars, Eickhoff, Jan, Hannus, Stefan, Hansen, Kerrin, Amon, Peter, Ivanov, Igor, Borgmann, Matthias, Smith, Chase, Kluge, Arthur F, Murthi, Krishan, Casaubon, Rebecca
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.