Method of obtaining idolocarbazoles using biosynthetic rebeccamycin genes
Saccharothrix aerocolonigenes Streptomyces Saccharothrix aerocolonigenes Streptomyces albusMethod for production of indolocarbazoles by using rebeccamycin biosynthetic genes. The invention is based on utilization of rebeccamycin biosynthetic genes from for production of indolocarbazoles in related m...
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| Sprache: | eng |
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| Zusammenfassung: | Saccharothrix aerocolonigenes Streptomyces Saccharothrix aerocolonigenes Streptomyces albusMethod for production of indolocarbazoles by using rebeccamycin biosynthetic genes. The invention is based on utilization of rebeccamycin biosynthetic genes from for production of indolocarbazoles in related microorganisms (spp.). Method includes the isolation of a DNA fragment from ATCC39243 containing the rebeccamycin biosynthesis gene cluster and the expression of these genes in , achieving production of rebeccamycin and derivatives. The invention is suitable for use in the pharmaceutical field. |
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