Method for the synthesis of a bifunctional complex

Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more rea...

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Bibliographische Detailangaben
Hauptverfasser: Freskgard, Per-Ola, Franch, Thomas, Gouliaev, Alex Haahr, Lundorf, Mikkel Dybro, Felding, Jakob, Olsen, Eva Kampmann, Holtmann, Anette, Jakobsen, Soeren Nyboe, Sams, Christian Klarner, Glad, Sanne Schroeder, Jensen, Kim Birkebaek, Pedersen, Henrik
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more reactants, and provided with respective tag(s) identifying the reactants(s) at the priming site using one or more enzymes.