Methods of controlling proliferation and differentiation of stem and progenitor cells

A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for per...

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Bibliographische Detailangaben
Hauptverfasser: Peled, Tony, Fibach, Eitan, Treves, Avi
Format: Patent
Sprache:eng
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Zusammenfassung:A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for permitting the stem cells to proliferate and, at the same time, for reducing a capacity of the stem cells to differentiate.