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131213 1234 5 14 214 The present invention is directed to the labeled compounds, wherein C* is each either C and C where at least one C* is C, each hydrogen of the methylene group is hydrogen or deuterium, the methyl group includes either zero or three deuterium atoms, Q is sulfide, sulfinyl, or sul...

Ausführliche Beschreibung

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Hauptverfasser: Martinez, Rodolfo A, Unkefer, Clifford J, Alvarez, Marc A
Format: Patent
Sprache:eng
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Zusammenfassung:131213 1234 5 14 214 The present invention is directed to the labeled compounds, wherein C* is each either C and C where at least one C* is C, each hydrogen of the methylene group is hydrogen or deuterium, the methyl group includes either zero or three deuterium atoms, Q is sulfide, sulfinyl, or sulfone, Z is an aryl group such as 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, or a phenyl group wherein R, R, R, Rand Rare each independently either hydrogen, a C-Clower alkyl, a halogen, and an amino group such as NH, NHR and NRR′ where R and R′ are each independently either a C-Clower alkyl, a phenyl, and an alkoxy group, and the methyl group can include either zero or three deuterium atoms. The present invention is also directed to the labeled compounds