Treatment of neurological disorders by dsRNA administration

The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compositions useful for such treatme...

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Bibliographische Detailangaben
Hauptverfasser: Dorn, Gabriele, Ganju, Pamposh, Hall, Jonathan, Hemmings, Maria Wanda, Wishart, William Leonard
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compositions useful for such treatment.