Composition and method for facilitating the internalization of a therapeutic agent into a cell

The present invention is a composition and method for facilitating the internalization of a therapeutic agent into a cell. Specifically, the invention relates to the use of the extracellular domain of basigin-2, cyclophilin, or anti-basigin-2 antibody or antibody fragment as a delivery moiety for in...

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Bibliographische Detailangaben
Hauptverfasser: Nowak, Romana A, Belton, Jr, Robert J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is a composition and method for facilitating the internalization of a therapeutic agent into a cell. Specifically, the invention relates to the use of the extracellular domain of basigin-2, cyclophilin, or anti-basigin-2 antibody or antibody fragment as a delivery moiety for internalization of a therapeutic agent.