Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof
The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods,...
Gespeichert in:
Hauptverfasser: | , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | Burright, Eric Neal Kaemmerer, William F Thakker, Deepak Ramesh Heisel, Jennifer |
description | The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies. |
format | Patent |
fullrecord | <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_08173614</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>08173614</sourcerecordid><originalsourceid>FETCH-uspatents_grants_081736143</originalsourceid><addsrcrecordid>eNqNjEEKwjAQRbNxIeod5gKCpaJuRRRXLqR7GdJJGmgzITO5v2nxAK4-7__PWxvfDZQxUdEQPVieEkvQwFEWyEHmHiO8X9cA6ClqpR4QIpXMmjkNwYJDq5yXZSIduBdgB0UItPqJ3dasHI5Cu19uDDzu3e25L5JQq1U-PuMch0tzbk_Nsf3j8gWBsEDd</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof</title><source>USPTO Issued Patents</source><creator>Burright, Eric Neal ; Kaemmerer, William F ; Thakker, Deepak Ramesh ; Heisel, Jennifer</creator><creatorcontrib>Burright, Eric Neal ; Kaemmerer, William F ; Thakker, Deepak Ramesh ; Heisel, Jennifer ; Medtronic, Inc</creatorcontrib><description>The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies.</description><language>eng</language><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173614$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64012</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8173614$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Burright, Eric Neal</creatorcontrib><creatorcontrib>Kaemmerer, William F</creatorcontrib><creatorcontrib>Thakker, Deepak Ramesh</creatorcontrib><creatorcontrib>Heisel, Jennifer</creatorcontrib><creatorcontrib>Medtronic, Inc</creatorcontrib><title>Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof</title><description>The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNjEEKwjAQRbNxIeod5gKCpaJuRRRXLqR7GdJJGmgzITO5v2nxAK4-7__PWxvfDZQxUdEQPVieEkvQwFEWyEHmHiO8X9cA6ClqpR4QIpXMmjkNwYJDq5yXZSIduBdgB0UItPqJ3dasHI5Cu19uDDzu3e25L5JQq1U-PuMch0tzbk_Nsf3j8gWBsEDd</recordid><startdate>20120508</startdate><enddate>20120508</enddate><creator>Burright, Eric Neal</creator><creator>Kaemmerer, William F</creator><creator>Thakker, Deepak Ramesh</creator><creator>Heisel, Jennifer</creator><scope>EFH</scope></search><sort><creationdate>20120508</creationdate><title>Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof</title><author>Burright, Eric Neal ; Kaemmerer, William F ; Thakker, Deepak Ramesh ; Heisel, Jennifer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_081736143</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Burright, Eric Neal</creatorcontrib><creatorcontrib>Kaemmerer, William F</creatorcontrib><creatorcontrib>Thakker, Deepak Ramesh</creatorcontrib><creatorcontrib>Heisel, Jennifer</creatorcontrib><creatorcontrib>Medtronic, Inc</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Burright, Eric Neal</au><au>Kaemmerer, William F</au><au>Thakker, Deepak Ramesh</au><au>Heisel, Jennifer</au><aucorp>Medtronic, Inc</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof</title><date>2012-05-08</date><risdate>2012</risdate><abstract>The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_uspatents_grants_08173614 |
source | USPTO Issued Patents |
title | Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T19%3A21%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Burright,%20Eric%20Neal&rft.aucorp=Medtronic,%20Inc&rft.date=2012-05-08&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E08173614%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |