Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof

The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods,...

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Bibliographische Detailangaben
Hauptverfasser: Burright, Eric Neal, Kaemmerer, William F, Thakker, Deepak Ramesh, Heisel, Jennifer
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides novel combination therapies for treating Huntington's disease which comprise a) BDNF or suitable fragments thereof and b) agents capable of causing inhibition of a gene responsible for the neurodegenerative disease. The invention provides nucleic acid sequences, methods, and systems suitable for applications of these combination therapies.