Nested permeable support device and method for using the nested permeable support device

A nested permeable support device is described herein that can be used to perform various experiments to test new therapeutic compounds (new chemical entities). In one application, the nested permeable support device is used to perform a first pass assay to determine the bioavailability of a new che...

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Bibliographische Detailangaben
Hauptverfasser: Martin, Gregory R, Tanner, Allison J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A nested permeable support device is described herein that can be used to perform various experiments to test new therapeutic compounds (new chemical entities). In one application, the nested permeable support device is used to perform a first pass assay to determine the bioavailability of a new chemical entity following absorption through the digestive tract and metabolism by the liver.