Process for pure montelukast sodium through pure intermediates as well as amine salts

The present invention provides an improved process for the preparation of highly pure montelukast sodium through highly pure diol intermediate compound of formula (2) and (1)-(mercapto methyl)cyclopropane acetic acid methyl ester compound of formula (4) or mercaptomethyl cyclopropane acetic acid com...

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Bibliographische Detailangaben
Hauptverfasser: Reddy, Manne Satyanarayana, Kumar, Muppa Kishore, Reddy, Karamala Rama Subba, Prasad, Durgadas Shyla
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides an improved process for the preparation of highly pure montelukast sodium through highly pure diol intermediate compound of formula (2) and (1)-(mercapto methyl)cyclopropane acetic acid methyl ester compound of formula (4) or mercaptomethyl cyclopropane acetic acid compound of formula (7). The present invention also provides novel organic amine salts of montelukast.