System and method of optical reading employing virtual scan lines

Optical reading system and methods having multiple modes of operation, for example: omnidirectional and single-code picking; fixed and handheld reading; 1D and 2D code reading. In one configuration, an image-based system obtains input data via an area sensor (e.g., a 2D CCD array) with only data corresponding to a pattern of virtual scan lines being stored and processed. A user may implement different operating modes such as a first mode reading codes in any location or orientation and a second mode reading only a code oriented along a particular virtual scan line or group thereof. Alternately, the data reader is operable to switch between handheld mode selecting a first pattern of virtual scan lines to process and/or decode and a fixed mode selecting a second pattern of virtual scan lines to process and/or decode. Virtual scan patterns in either mode can change within or between frames.