Acellular dermal matrix and method of use thereof for grafting

A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment...

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Bibliographische Detailangaben
Hauptverfasser: Livesey, Stephen A, del Campo, Anthony A, Nag, Abhijit, Nichols, Ken B, Griffey, Edward S, Coleman, Christopher
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.