Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel

Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel

12345678910 11 A compound of Formula I in free or salt or solvate form, where R, R, R, R, R, R, R, R, R, Rand Rhave the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain...

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Hauptverfasser: Bhalay, Gurdip, Budd, Emma, Bloomfield, Graham Charles, Collingwood, Stephen Paul, Dunstan, Andrew, Edwards, Lee, Gedeck, Peter, Howsham, Catherine, Hunt, Peter, Hunt, Thomas Anthony, Oakley, Paul, Smith, Nichola
Format: Patent
Sprache:eng
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Zusammenfassung:12345678910 11 A compound of Formula I in free or salt or solvate form, where R, R, R, R, R, R, R, R, R, Rand Rhave the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.