HIV replication inhibiting purine derivatives

1717The present invention relates to the use of a compound of formula (I) for the manufacture of a medicament for the prevention or the treatment of HIV infection wherein the compound of formula (I) is a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine o...

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Bibliographische Detailangaben
Hauptverfasser: Janssen, Paul Adriaan Jan, Lewi, Paulus Joannes, de Jonge, Marc René, Koymans, Lucien Maria Henricus, Daeyaert, Frederik Frans Desiré, Heeres, Jan, Vinkers, Hendrik Maarten, Leenders, Ruben Gerardus George, Vandenput, Dirk Alfons Leo
Format: Patent
Sprache:eng
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Zusammenfassung:1717The present invention relates to the use of a compound of formula (I) for the manufacture of a medicament for the prevention or the treatment of HIV infection wherein the compound of formula (I) is a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine or a stereochemically isomeric form thereof, wherein A and B each represents a radical of formula and wherein -C-D- represents a bivalent radical of formula -N═CH-NR-  (c-1); or -NR-CH═N-  (c-2); provided that when A represents a radical of formula (a) then B represents a radical of formula (b) and when A represents a radical of formula (b) then B represents a radical of formula (a).