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Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.

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Bibliographische Detailangaben
Hauptverfasser: Callewaert, Nico Luc Marc, Vervecken, Wouter, De Pourcq, Karen Jacqueline Marcel, Geysens, Steven Christian Jozef, Guerfal, Mouna
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
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Beschreibung
Zusammenfassung:Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.