Solution-phase synthesis of leuprolide and its intermediates

A process for producing a nonapeptide leuprolide and an intermediate N-protected oligopetides, wherein at least one peptide bond of the compound is formed by reacting an activated carboxylic acid and an amine component in a continuous flow.

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Hauptverfasser:	Kadzimirsz, Daniel, Jas, Gerhard, Autze, Volker
Format:	Patent
Sprache:	eng
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creator	Kadzimirsz, Daniel Jas, Gerhard Autze, Volker
description	A process for producing a nonapeptide leuprolide and an intermediate N-protected oligopetides, wherein at least one peptide bond of the compound is formed by reacting an activated carboxylic acid and an amine component in a continuous flow.
format	Patent
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title	Solution-phase synthesis of leuprolide and its intermediates
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