Heterobicyclic thiophene compounds and methods of use

Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Blake, James F, Boyd, Steven, De Meese, Jason, Gaudino, John J, Marlow, Allison L, Seo, Jeongbeob, Thomas, Allen A, Tian, Hongqi
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Blake, James F
Boyd, Steven
De Meese, Jason
Gaudino, John J
Marlow, Allison L
Seo, Jeongbeob
Thomas, Allen A
Tian, Hongqi
description Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
format Patent
fullrecord <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_08003662</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>08003662</sourcerecordid><originalsourceid>FETCH-uspatents_grants_080036623</originalsourceid><addsrcrecordid>eNrjZDD1SC1JLcpPykyuTM7JTFYoycjML8hIzUtVSM7PLcgvzUspVkjMS1HITS3JyAey89MUSotTeRhY0xJzilN5oTQ3g4Kba4izh25pcUFiSWpeSXF8elEiiDKwMDAwNjMzMiZCCQBgxi5K</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Heterobicyclic thiophene compounds and methods of use</title><source>USPTO Issued Patents</source><creator>Blake, James F ; Boyd, Steven ; De Meese, Jason ; Gaudino, John J ; Marlow, Allison L ; Seo, Jeongbeob ; Thomas, Allen A ; Tian, Hongqi</creator><creatorcontrib>Blake, James F ; Boyd, Steven ; De Meese, Jason ; Gaudino, John J ; Marlow, Allison L ; Seo, Jeongbeob ; Thomas, Allen A ; Tian, Hongqi ; Array BioPharma, Inc</creatorcontrib><description>Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.</description><language>eng</language><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8003662$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64016</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8003662$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Blake, James F</creatorcontrib><creatorcontrib>Boyd, Steven</creatorcontrib><creatorcontrib>De Meese, Jason</creatorcontrib><creatorcontrib>Gaudino, John J</creatorcontrib><creatorcontrib>Marlow, Allison L</creatorcontrib><creatorcontrib>Seo, Jeongbeob</creatorcontrib><creatorcontrib>Thomas, Allen A</creatorcontrib><creatorcontrib>Tian, Hongqi</creatorcontrib><creatorcontrib>Array BioPharma, Inc</creatorcontrib><title>Heterobicyclic thiophene compounds and methods of use</title><description>Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZDD1SC1JLcpPykyuTM7JTFYoycjML8hIzUtVSM7PLcgvzUspVkjMS1HITS3JyAey89MUSotTeRhY0xJzilN5oTQ3g4Kba4izh25pcUFiSWpeSXF8elEiiDKwMDAwNjMzMiZCCQBgxi5K</recordid><startdate>20110823</startdate><enddate>20110823</enddate><creator>Blake, James F</creator><creator>Boyd, Steven</creator><creator>De Meese, Jason</creator><creator>Gaudino, John J</creator><creator>Marlow, Allison L</creator><creator>Seo, Jeongbeob</creator><creator>Thomas, Allen A</creator><creator>Tian, Hongqi</creator><scope>EFH</scope></search><sort><creationdate>20110823</creationdate><title>Heterobicyclic thiophene compounds and methods of use</title><author>Blake, James F ; Boyd, Steven ; De Meese, Jason ; Gaudino, John J ; Marlow, Allison L ; Seo, Jeongbeob ; Thomas, Allen A ; Tian, Hongqi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_080036623</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Blake, James F</creatorcontrib><creatorcontrib>Boyd, Steven</creatorcontrib><creatorcontrib>De Meese, Jason</creatorcontrib><creatorcontrib>Gaudino, John J</creatorcontrib><creatorcontrib>Marlow, Allison L</creatorcontrib><creatorcontrib>Seo, Jeongbeob</creatorcontrib><creatorcontrib>Thomas, Allen A</creatorcontrib><creatorcontrib>Tian, Hongqi</creatorcontrib><creatorcontrib>Array BioPharma, Inc</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Blake, James F</au><au>Boyd, Steven</au><au>De Meese, Jason</au><au>Gaudino, John J</au><au>Marlow, Allison L</au><au>Seo, Jeongbeob</au><au>Thomas, Allen A</au><au>Tian, Hongqi</au><aucorp>Array BioPharma, Inc</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Heterobicyclic thiophene compounds and methods of use</title><date>2011-08-23</date><risdate>2011</risdate><abstract>Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_grants_08003662
source USPTO Issued Patents
title Heterobicyclic thiophene compounds and methods of use
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T11%3A21%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Blake,%20James%20F&rft.aucorp=Array%20BioPharma,%20Inc&rft.date=2011-08-23&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E08003662%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true