Heterobicyclic thiophene compounds and methods of use

Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis,...

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Bibliographische Detailangaben
Hauptverfasser: Blake, James F, Boyd, Steven, De Meese, Jason, Gaudino, John J, Marlow, Allison L, Seo, Jeongbeob, Thomas, Allen A, Tian, Hongqi
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.