Inhibitors of L1 and ADAM10 for the treatment of carcinomas

Described is a pharmaceutical composition comprising a compound(s) interfering with the biological activity of L1 and/or ADAM10 or their expression. Also described is the use of said compound(s) for the prevention/treatment of carcinomas like ovarian and endometrial carcinoma. Finally, the diagnosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Altevogt, Peter, Kelm, Daniela, Fogel, Mina
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Described is a pharmaceutical composition comprising a compound(s) interfering with the biological activity of L1 and/or ADAM10 or their expression. Also described is the use of said compound(s) for the prevention/treatment of carcinomas like ovarian and endometrial carcinoma. Finally, the diagnosis of highly malignant forms of carcinomas which is based on the determination of the activity/expression of L1 and/or ADAM10 is described.