Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors

Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors

Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such composi...

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Bibliographische Detailangaben
Hauptverfasser: Bosch, H. William, Cary, Greta G, Hovey, Douglas C, Jain, Rajeev A, Kline, Laura J, Merisko-Liversidge, Elaine, Ostrander, Kevin D, Ryde, Niels P, Ruddy, Stephen B
Format: Patent
Sprache:eng
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Zusammenfassung:Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.