NOGO-a neutralising immunoglobulin for treatment of neurological diseases

NOGO-a neutralising immunoglobulin for treatment of neurological diseases

The present invention provides immunoglobulins, particularly antibodies that bind to NOGO and neutralise the activity thereof, polynucleotides encoding such antibodies, pharmaceutical formulations containing said antibodies and to the use of such antibodies in the treatment and/or prophylaxis of neu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ellis, Jonathan Henry, Eon-Duval, Alexandre, Grundy, Robert Ian, Hussain, Farhana, McAdam, Ruth, Plumpton, Christopher, Prinjha, Rabinder Kumar, Wilson, Paul Alexander
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides immunoglobulins, particularly antibodies that bind to NOGO and neutralise the activity thereof, polynucleotides encoding such antibodies, pharmaceutical formulations containing said antibodies and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases.