Binding moieties based on shark ignar domains

The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural featu...

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Bibliographische Detailangaben
Hauptverfasser:	Nuttal, Stewart, Streltsov, Victor, Griffiths, Katherine Merne, Carmichael, Jennifer Ann, Hudson, Peter, Irving, Robert Alexander, Varghese, Joseph Noozhumurry, Barraclough, Miles Mackay, Simmons, David Peter, Henderson, Kylie Anne
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.