Hydrolytically-resistant boron-containing therapeutics and methods of use

Hydrolytically-resistant boron-containing therapeutics and methods of use

Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

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Bibliographische Detailangaben
Hauptverfasser: Lee, Ving, Plattner, Jacob J, Benkovic, Stephen J, Baker, Stephen J, Maples, Kirk R, Bellinger-Kawahara, Carolyn, Akama, Tsutomu, Zhang, Yong-Kang, Singh, Rajeshwar, Sauro, Vittorio A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.