Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one

1b The present invention relates to a process of the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one of the formula by employing a dialkylmalonate of the formula wherein Ris lower alkyl, and the use of this process for the manufacture of DPP-IV inhibitors that are useful for the treatment and/...

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Bibliographische Detailangaben
1. Verfasser: Zutter, Ulrich
Format: Patent
Sprache:eng
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Zusammenfassung:1b The present invention relates to a process of the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one of the formula by employing a dialkylmalonate of the formula wherein Ris lower alkyl, and the use of this process for the manufacture of DPP-IV inhibitors that are useful for the treatment and/or prophylaxis of diseases such as diabetes.