N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases

12345678910111213The present invention provides N-cyclohexyl benzamide and benzeneacetamide compounds according to formula (I): where R, R, R, R, R, R, R, R, R, R, R, R, R, m, n, p, and q are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of...

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Hauptverfasser: Yuan, Chester Chenguang, Han, Nianhe, Liu, Qingyian, McMinn, Dustin, Powers, Jay
Format: Patent
Sprache:eng
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Zusammenfassung:12345678910111213The present invention provides N-cyclohexyl benzamide and benzeneacetamide compounds according to formula (I): where R, R, R, R, R, R, R, R, R, R, R, R, R, m, n, p, and q are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of the compounds and compositions of the invention for the treatment of conditions associated with hydroxysteroid dehydrogenases (e.g., 11β-HSD1), and the use of the compounds of the invention in the preparation of medicaments for the treatment of hydroxysteroid dehydrogenase-associated conditions.