Humanized anti-amyloid beta antibodies
Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Shafer, Lisa Lynn Carr, Francis Joseph Gregson, James Peter Bembridge, Dawn Ann Jones, Tim |
| description | Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody. |
| format | Patent |
| fullrecord | <record><control><sourceid>uspatents_EFH</sourceid><recordid>TN_cdi_uspatents_grants_07931899</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>07931899</sourcerecordid><originalsourceid>FETCH-uspatents_grants_079318993</originalsourceid><addsrcrecordid>eNrjZFDzKM1NzMusSk1RSMwrydRNzK3Myc9MUUhKLUkEiyTlp2SmFvMwsKYl5hSn8kJpbgYFN9cQZw_d0uKCxJLUvJLi-PSiRBBlYG5pbGhhaWlMhBIAVpkoog</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Humanized anti-amyloid beta antibodies</title><source>USPTO Issued Patents</source><creator>Shafer, Lisa Lynn ; Carr, Francis Joseph ; Gregson, James Peter ; Bembridge, Dawn Ann ; Jones, Tim</creator><creatorcontrib>Shafer, Lisa Lynn ; Carr, Francis Joseph ; Gregson, James Peter ; Bembridge, Dawn Ann ; Jones, Tim ; Medtronic, Inc</creatorcontrib><description>Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.</description><language>eng</language><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7931899$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,802,885,64037</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7931899$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Shafer, Lisa Lynn</creatorcontrib><creatorcontrib>Carr, Francis Joseph</creatorcontrib><creatorcontrib>Gregson, James Peter</creatorcontrib><creatorcontrib>Bembridge, Dawn Ann</creatorcontrib><creatorcontrib>Jones, Tim</creatorcontrib><creatorcontrib>Medtronic, Inc</creatorcontrib><title>Humanized anti-amyloid beta antibodies</title><description>Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNrjZFDzKM1NzMusSk1RSMwrydRNzK3Myc9MUUhKLUkEiyTlp2SmFvMwsKYl5hSn8kJpbgYFN9cQZw_d0uKCxJLUvJLi-PSiRBBlYG5pbGhhaWlMhBIAVpkoog</recordid><startdate>20110426</startdate><enddate>20110426</enddate><creator>Shafer, Lisa Lynn</creator><creator>Carr, Francis Joseph</creator><creator>Gregson, James Peter</creator><creator>Bembridge, Dawn Ann</creator><creator>Jones, Tim</creator><scope>EFH</scope></search><sort><creationdate>20110426</creationdate><title>Humanized anti-amyloid beta antibodies</title><author>Shafer, Lisa Lynn ; Carr, Francis Joseph ; Gregson, James Peter ; Bembridge, Dawn Ann ; Jones, Tim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_079318993</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Shafer, Lisa Lynn</creatorcontrib><creatorcontrib>Carr, Francis Joseph</creatorcontrib><creatorcontrib>Gregson, James Peter</creatorcontrib><creatorcontrib>Bembridge, Dawn Ann</creatorcontrib><creatorcontrib>Jones, Tim</creatorcontrib><creatorcontrib>Medtronic, Inc</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Shafer, Lisa Lynn</au><au>Carr, Francis Joseph</au><au>Gregson, James Peter</au><au>Bembridge, Dawn Ann</au><au>Jones, Tim</au><aucorp>Medtronic, Inc</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Humanized anti-amyloid beta antibodies</title><date>2011-04-26</date><risdate>2011</risdate><abstract>Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_uspatents_grants_07931899 |
| source | USPTO Issued Patents |
| title | Humanized anti-amyloid beta antibodies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T02%3A42%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFH&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Shafer,%20Lisa%20Lynn&rft.aucorp=Medtronic,%20Inc&rft.date=2011-04-26&rft_id=info:doi/&rft_dat=%3Cuspatents_EFH%3E07931899%3C/uspatents_EFH%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |