CXCR2 inhibitors

CXCR2 inhibitors

The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hachtel, Stephanie, Dedio, Juergen, Heitsch, Holger, Czechtizky, Werngard, Grueneberg, Sven, Shimshock, Stephen J, Kosley, Jr, Raymond W, Lanter, Carolina L, Li, Hui, Sher, Rosy, Weichsel, Aleksandra
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.