Transdermal delivery of (R)-3,3-diphenylpropylamin-monoestern

1-43-101-3 The invention relates to a device for transdermally administering a compound of formula (I), wherein A represents hydrogen or deuterium, R represents a group selected among Calkyl, Ccycloalkyl, or phenyl, each of which can be substituted by Calkoxy, fluoride, chlorine, bromine, iodine, ni...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Breitenbach, Armin, Meese, Claus, Wolff, Hans-Michael, Drews, Roland
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:1-43-101-3 The invention relates to a device for transdermally administering a compound of formula (I), wherein A represents hydrogen or deuterium, R represents a group selected among Calkyl, Ccycloalkyl, or phenyl, each of which can be substituted by Calkoxy, fluoride, chlorine, bromine, iodine, nitro, amino, hydroxy, oxo, mercapto, or deuterium, the C atom marked by * (asterisk) being provided in the R configuration. The invention is characterized in that the compound of general formula (I) is provided in a polymer matrix and is released at a dose of 0.5 to 20 mg per day through human skin. The invention further relates to the use of said compounds of formula (I) for producing transdermal medicaments.