Dendrimeric peptides, pharmaceutical compositions and methods of using the same

Novel dendrimeric peptide compounds are disclosed that have a formula represented by the following formula I: The compounds demonstrate antimicrobial activity and may be prepared as pharmaceutical compositions and used for the prevention and treatment of a variety of conditions in mammals including...

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Hauptverfasser: Kallenbach, Neville Robert, Young, Anne W, Liu, Zhigang, Zhou, Chunhui
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Novel dendrimeric peptide compounds are disclosed that have a formula represented by the following formula I: The compounds demonstrate antimicrobial activity and may be prepared as pharmaceutical compositions and used for the prevention and treatment of a variety of conditions in mammals including humans where microbial invasion is involved. The present peptides are particularly valuable as their effect is rapid, broad in spectrum and mostly indifferent to resistance provoked by standard antibiotics.