Process for the preparation of phenylcarbamates

1 2 1-6 3 4 3 4 5 6 1-6 5 6 This invention relates to a process for the preparation of an aminoalkyl phenyl carbamate compound of formula 1, wherein Rand Rindependently are hydrogen or Calkyl; Rand Rare the same or different and each is a lower alkyl; or Rand Rtogether with the nitrogen to which the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Raheem, Mohammed Abdul, Wang, Zhi-Xian, Wolf, Eckardt C. G
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:1 2 1-6 3 4 3 4 5 6 1-6 5 6 This invention relates to a process for the preparation of an aminoalkyl phenyl carbamate compound of formula 1, wherein Rand Rindependently are hydrogen or Calkyl; Rand Rare the same or different and each is a lower alkyl; or Rand Rtogether with the nitrogen to which they are attached form a cyclic moiety of a three to eight-member ring, with or without a hetero atom like nitrogen or oxygen; Rand Rindependently are hydrogen, linear, branched or cyclic Calkyl, allyl, propargyl or benzyl; or Rand Rtogether with the nitrogen to which they are attached form a cyclic moiety of three to eight member ring, with or without a hetero atom like nitrogen or oxygen; the carbon center marked with "*" is racemic or enantiomerically enriched (R)- or (S)-configuration; and pharmaceutically acceptable addition salts, and crystalline and amorphous forms thereof comprising the steps of: