Chromatography ligand

12345 1 2 3 4 5 The present invention relates to a chromatography ligand defined by the following formula (I) R-R-N(R)-R-Rwherein Ris a substituted or non-substituted phenyl group; Ris a hydrocarbon chain comprising 0-4 carbon atoms; Ris a hydrocarbon chain comprising 1-3 carbon atoms; Ris a hydroca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Engstrand, Carina, Forss, Annika, Glad, Gunnar, Johansson, Bo-Lennart, Johansson, Hans J, Maloisel, Jean-Luc
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:12345 1 2 3 4 5 The present invention relates to a chromatography ligand defined by the following formula (I) R-R-N(R)-R-Rwherein Ris a substituted or non-substituted phenyl group; Ris a hydrocarbon chain comprising 0-4 carbon atoms; Ris a hydrocarbon chain comprising 1-3 carbon atoms; Ris a hydrocarbon chain comprising 1-5 carbon atoms; and Ris OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.