Pyrimidineamines as angiogenesis modulators

Pyrimidineamines as angiogenesis modulators

Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

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Bibliographische Detailangaben
Hauptverfasser: Boloor, Amogh, Cheung, Mui, Davis-Ward, Ronda Gayle, Harris, Philip Anthony, Hinkle, Kevin, Lauderman, Christopher P, Mook, Jr, Robert Anthony, Stafford, Jeffery Alan, Veal, James Marvin
Format: Patent
Sprache:eng
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Zusammenfassung:Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.