Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof

The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cargill, Michele, Begovich, Ann Bethea, Alexander, Heather Camille
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.