Radioactive arsenic-containing compounds and their uses in the treatment of tumors
232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a...
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| creator | Lee, Te-Wei Huang, Chun-Ying Wu, Ming-Shiuan Chen, Te-Jung Chang, Kwo-Ping Chang, Shiang-Rong Chyi, Shyh-Yi Chang, Chih-Hsien Hsu, Yin-Mao Fan, Kuo-Hsien Hsu, Wei-Chuan Fu, Ying-Kai Kao, Charng-Feng |
| description | 232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i).This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors. |
| format | Patent |
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The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors.</description><language>eng</language><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7803350$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,776,798,881,64012</link.rule.ids><linktorsrc>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7803350$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Lee, Te-Wei</creatorcontrib><creatorcontrib>Huang, Chun-Ying</creatorcontrib><creatorcontrib>Wu, Ming-Shiuan</creatorcontrib><creatorcontrib>Chen, Te-Jung</creatorcontrib><creatorcontrib>Chang, Kwo-Ping</creatorcontrib><creatorcontrib>Chang, Shiang-Rong</creatorcontrib><creatorcontrib>Chyi, Shyh-Yi</creatorcontrib><creatorcontrib>Chang, Chih-Hsien</creatorcontrib><creatorcontrib>Hsu, Yin-Mao</creatorcontrib><creatorcontrib>Fan, Kuo-Hsien</creatorcontrib><creatorcontrib>Hsu, Wei-Chuan</creatorcontrib><creatorcontrib>Fu, Ying-Kai</creatorcontrib><creatorcontrib>Kao, Charng-Feng</creatorcontrib><creatorcontrib>Institute of Nuclear Energy Research Rocaec</creatorcontrib><creatorcontrib>TTY Biopharm Company, Limited</creatorcontrib><title>Radioactive arsenic-containing compounds and their uses in the treatment of tumors</title><description>232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i).This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EFH</sourceid><recordid>eNqNykEKwkAMQNHZuBD1DrlAYWAQ3YvFdXEvYSatAZuUScbza8EDuHp8-NswDFhYMTu_CbAaCecuqziysEyQdV60STFAKeBP4grNyIBlLfBK6DOJg47gbdZq-7AZ8WV0-LkL0F_vl1vXbEH_rvaYKq7E0zmmdIzpj-UDDsw5VA</recordid><startdate>20100928</startdate><enddate>20100928</enddate><creator>Lee, Te-Wei</creator><creator>Huang, Chun-Ying</creator><creator>Wu, Ming-Shiuan</creator><creator>Chen, Te-Jung</creator><creator>Chang, Kwo-Ping</creator><creator>Chang, Shiang-Rong</creator><creator>Chyi, Shyh-Yi</creator><creator>Chang, Chih-Hsien</creator><creator>Hsu, Yin-Mao</creator><creator>Fan, Kuo-Hsien</creator><creator>Hsu, Wei-Chuan</creator><creator>Fu, Ying-Kai</creator><creator>Kao, Charng-Feng</creator><scope>EFH</scope></search><sort><creationdate>20100928</creationdate><title>Radioactive arsenic-containing compounds and their uses in the treatment of tumors</title><author>Lee, Te-Wei ; Huang, Chun-Ying ; Wu, Ming-Shiuan ; Chen, Te-Jung ; Chang, Kwo-Ping ; Chang, Shiang-Rong ; Chyi, Shyh-Yi ; Chang, Chih-Hsien ; Hsu, Yin-Mao ; Fan, Kuo-Hsien ; Hsu, Wei-Chuan ; Fu, Ying-Kai ; Kao, Charng-Feng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_grants_078033503</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2010</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Lee, Te-Wei</creatorcontrib><creatorcontrib>Huang, Chun-Ying</creatorcontrib><creatorcontrib>Wu, Ming-Shiuan</creatorcontrib><creatorcontrib>Chen, Te-Jung</creatorcontrib><creatorcontrib>Chang, Kwo-Ping</creatorcontrib><creatorcontrib>Chang, Shiang-Rong</creatorcontrib><creatorcontrib>Chyi, Shyh-Yi</creatorcontrib><creatorcontrib>Chang, Chih-Hsien</creatorcontrib><creatorcontrib>Hsu, Yin-Mao</creatorcontrib><creatorcontrib>Fan, Kuo-Hsien</creatorcontrib><creatorcontrib>Hsu, Wei-Chuan</creatorcontrib><creatorcontrib>Fu, Ying-Kai</creatorcontrib><creatorcontrib>Kao, Charng-Feng</creatorcontrib><creatorcontrib>Institute of Nuclear Energy Research Rocaec</creatorcontrib><creatorcontrib>TTY Biopharm Company, Limited</creatorcontrib><collection>USPTO Issued Patents</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Lee, Te-Wei</au><au>Huang, Chun-Ying</au><au>Wu, Ming-Shiuan</au><au>Chen, Te-Jung</au><au>Chang, Kwo-Ping</au><au>Chang, Shiang-Rong</au><au>Chyi, Shyh-Yi</au><au>Chang, Chih-Hsien</au><au>Hsu, Yin-Mao</au><au>Fan, Kuo-Hsien</au><au>Hsu, Wei-Chuan</au><au>Fu, Ying-Kai</au><au>Kao, Charng-Feng</au><aucorp>Institute of Nuclear Energy Research Rocaec</aucorp><aucorp>TTY Biopharm Company, Limited</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Radioactive arsenic-containing compounds and their uses in the treatment of tumors</title><date>2010-09-28</date><risdate>2010</risdate><abstract>232322This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of AsO, AsS, AsS, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i).This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Radioactive arsenic-containing compounds and their uses in the treatment of tumors |
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